Enzymes

General

• Biochemistry Online: An Approach Based on Chemical Logic - Biochemistry within the framework of chemical principles and logic. (Henry Jakubowski, College of St. Benedict/St. John's University)
  • Cofactors and Electron Pushing: Sources and Sink
  • Enzyme-Catalyzed Reactions in Organic Solvents
  • Methods of Catalysis
  • Mechanisms of Enzyme-Catalyzed Reactions
  • Models of Enzyme Inhibition
  • More Complicated Enzymes
  • Rapid Equilibrium and Steady State Enzyme Kinetics - Derivations
  • Review of Organic Chemistry
  • Ribozymes
• The Biology Project: Biochemistry - Tutorial on basic biochemistry. (University of Arizona) (Beginner's Level)
• From Protein Science to Enzymology - Basic lectures on enzymology. (John E. Wampler, University of Georgia) (Just above Beginner's Level)
• Kimball's Biology Pages - Mini-essays on a number of biological topics with a lot of cell biology. (Beginner's Level)
  • Enzyme Kinetics - Basic introduction to enzyme kinetics.
  • Enzymes - Basic introduction to enzymes.
• The Medical Biochemistry Page: Enzymes - Introduction to enzyme kinetics. (Michael W. King, Indiana University School of Medicine)
• Much Ado about Enzyme Mechanisms - Article in the Feb. 23, 2004 issue of Chemical and Engineering News on recent advances in understanding how enzymes work. (Stu Borman)
• On-Line Biology Book - Comprehensive introduction to biology at the "college freshman" level by Michael J. Farabee. (Beginner's Level)
  • Laws of Thermodynamics
  • Reactions and Enzymes
• Wikipedia - Free online encyclopedia with basic overviews. (Beginner's Level)
  • Catalyst
  • Enzymes

See also the Chemical Biology, Metabolism, Cellular Respiration and Photosynthesis, Proteins: Biogenesis to Degradation and Structural Biology pages.

Enzyme Databases (Collections of Enzyme Functional and Nomenclature Data)

• CAZy (Carbohydrate-Active Enzymes) - "The CAZy database describes the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds." (Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, France)
• Enzyme Database - BRENDA - A "collection of enzyme functional data available to the scientific community." (Cologne University Bioinformatics Center, Germany)
• ExPASy - ENZYME - Enzyme nomenclature database.
• International Union of Biochemistry and Molecular Biology (IUBMB)
  • Enzyme Nomenclature
  • IUBMB Nomenclature
  • Symbolism and Terminology in Enzyme Kinetics
• MEROPS - The Peptidase Database - "The MEROPS database is an information resource for peptidases (also termed proteases, proteinases and proteolytic enzymes) and the proteins that inhibit them." (Neil D. Rawlings, Fraser R. Morton and Alan J. Barrett, Wellcome Trust Sanger Institute, Cambridge, UK)
• Restriction Enzyme Database (REBASE) - Comprehensive database of information on restriction enzymes.
• SABIO Reaction Kinetics Database - "The SABIO-RK (System for the Analysis of Biochemical Pathways - Reaction Kinetics) is a web-based application based on the SABIO relational database that contains information about biochemical reactions, their kinetic equations with their parameters, and the experimental conditions under which these parameters were measured."

Specific Enzymes

• Cytochrome P450 Homepage (David Nelson, University of Tennessee, Health Science Center)
• Enzymology of Cytochrome P450 Reductase (Todd D. Porter, University of Kentucky College of Pharmacy)

Protein and Proteomics Databases

Macromolecular Structure Databases

Discussion Groups

• BioChemWeb.org Discussion Board - Discussions and questions/answers for scientists and students.

See also the Discussion Groups section of the General Resources and Tutorials page.

Labs Studying Enzymes